Abstract: Osteoarthritis is a most common reason of joint disability over 45 years of age. It is the main cause of dysfunction in most countries around the world. Depending on functional activity limitations, an effective comprehensive rehabilitation program can be planned for the management of OA knee. Therefore, this study was conducted to know functional activity limitations in an Indian lifestyle. This cross- sectional study included 499 individuals who met inclusion criteria. It was conducted for 4 months in outpatient department of tertiary care hospital. The level of difficulty in sixteen chosen activities suitable mainly for Indian lifestyle was assessed. Analysis of data showed that sit to stand, getting in and out of the bed, sitting on the floor and getting up, cross sitting, climbing down stairs and sitting for a long time are the activities which are severely affected. Household chores and travelling via public transport are activities which are less affected mainly in people who follow Indian lifestyle