Abstract: Background: Osteoarthritis is a chronic disease of the joint cartilage and bone, often thought to result from “wear and tear” on a joint. Reflexology is the technique of applying pressure to the reflexes on the feet or hands in order to stimulate body’s own healing processes. Reflex area on feet and hands are linked to other areas and organs of the body within the same zone. Objective: To study the effect of BURST TENS on the reflexology points in patients with osteoarthritis knee. Methodology: Experimental type of study wherein the 30 patients were divided into groups randomly. Experimental group were given burst tens (30minutes on 80Hz and intensity as tolerated by patient for 10 sessions) on the reflexology points on hands (PIP joints of middle and ring fingers of both the hands) along with medications whereas control group were given only medications. The vas, rom and lequesne scale score was taken before and after the treatment. Results and Analysis: The results showed that there was significant improvement in range of motion and reduction in vas and Lequesne scale score for the experimental group.